Cardiovascular magnetic resonance follow-up of the Marfan's thoracic aorta after personalized external aortic root support surgery
نویسندگان
چکیده
Background Recently, personalized external aortic root support (PEARS) has been proposed as an alternative prophylactic surgery to prevent dilatation of the aortic root and dissection in Marfan syndrome patients. Briefly, a model of each patient’s aortic root and ascending aorta is created based on cardiac magnetic resonance (CMR) images. The model is then used to produce a bespoke external aortic root support made up of polymer mesh for each patient ready for surgical implantation[1]. The surgery is quicker than conventional aortic root replacement without the need for cardiopulmonary bypass or circulatory arrest. In addition, the blood endothelium interface is not interrupted and the native aortic valve is preserved obviating the need for life-long anticoagulation. Early positive result have been acknowledged in a recent NICE guidance document[2,3]. The aim of this study is to assess long term changes in aortic dimensions following PEARS surgery.
منابع مشابه
Effect of personalized external aortic root support on aortic root motion and distension in Marfan syndrome patients.
OBJECTIVE Personalized external aortic root support (PEARS) is a novel surgical approach with the aim of stabilizing the aortic root size and decreasing risk of dissection in Marfan syndrome patients. A bespoke polymer mesh tailored to each patient's individual aorta shape is produced by modeling and then surgically implanted. The aim of this study is to assess the mechanical effects of PEARS o...
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OBJECTIVES Conflicting results have been reported on late aortic growth and complication rates of the descending thoracic aorta in patients with Marfan syndrome (MFS) after proximal aortic surgery. METHODS Of 198 Marfan patients followed up regularly, 121 (43% David-I, 7% David-II, 11% supracoronary replacement, 52% mechanical conduit, 8% arch replacement) were analysed after proximal aortic ...
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A 52 year-old man underwent aortic valve replacement and ascending aortic replacement (Wheat procedure) for acute dissection (Stanford type A) and aortic regurgitation (grade 3/4). At that time, the aortic root was slightly dilated at about 45 mm and the descending aorta was within a normal range at about 35 mm. Forty months after the initial operation, a follow-up chest enhanced computed tomog...
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In 2008, a 26-year old man had personalized external aortic root support (PEARS) with a macroporous mesh. He was the 16th of 46 patients to have this operation. He had a typical Marfan habitus. His mother died of this disease as did his brother, with an aortic dissection. The patient himself died suddenly 4.5 years after his PEARS operation. At autopsy, there was no blood in the pericardium. Th...
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